Biosafety cabinet classification can be a delicate thing. This is not something that can be done quickly or without great care. When biological safety cabinet testing
is needed, it means that some complex work will be happening that is entirely dependent on the right conditions being present in the atmosphere of the new cabinet. In order to commission such a space, the following requirements must be in place.
Secure HVAC Systems
This is the most important aspect to check out. The HVAC system for the entire building will not be secure enough to work with these biosafety zones. You will need a separate system in order to make things work well. There can be no contamination whatsoever with the air coming to and from other non-secure areas in the building. New testing should be done on this system regularly to ensure there is no crossover happening.
There are a lot of small organisms that can enter these spaces despite how much care is taken to avoid contamination. The area needs to be cleaned and completely sterilized on a regular basis. There are tests that can be done to look for such growth, but following good hygiene and room cleaning steps will generally be enough to maintain the necessary sterile zone.
In order for a space to keep its biosafety commission, it will need to be restricted to use only by those engaged in the work for which the biosafety cabinet was created. This will require a working lock on the door. Most facilities will create locks with digital combinations that are only shared with those able and allowed to work on the project. Other key-centered locks can be sufficient, though. As long as the room is kept secure and inaccessible to those not involved, the system will work well.
Each facility and company will have their own protective steps and rules in place. These lines of protocol need to be followed faithfully by all who enter and use the room. A failure to do so can cause the cabinet to lose its biosafety classification, and certain elements of the work will have to be started again from scratch.
While this can be an intimidating process to work with, it is also something that can and has produced great results when followed well. The most important step to keeping a biosafety classification on any cabinet is to ensure that all involved personnel is taking the project seriously. This dedication to the goals of the project will best direct the actions of those involved.