What You Need to Know about Biosafety Cabinet Certification

Written by ATSC230@545404 on . Posted in WordPress

Because of critical work in pharmaceuticals, microbiology, and nanotechnology, the International Standards Organization established ISO classification standards. To assure safety, it's essential that biosafety cabinets (BSC) and clean rooms be certified.

Certification verifies that a biosafety cabinet provides the necessary safety and protection. Here are some things to know:


To verify that a BSC meets all requirements, testing should be conducted by professionals certified by an accredited institution. This means cabinets should be tested for leaks, that inflow and down flow velocity be checked, as well as airflow smoke patterns. HEPA filters should be scanned for leaks. You may also want to check lighting intensity, noise Levels, electrical elements, and vibration levels, although these are optional.


Routine maintenance of biosafety cabinets should be done by laboratory staff. Staff should decontaminate a cabinet's interior by wiping down all accessible surfaces with an appropriate disinfectant once the day's work is completed. They should disinfect the drain pan at least once a month, or more frequently if necessary.

Decontamination services should be used to fumigate the entire cabinet, including the blower/motor and HEPA filters, before repairs are done if potentially contaminated areas of the cabinet, including HEPA filter or motor/blower replacements must be accessed.


The entire biosafety cabinet must be decontaminated before it is moved to a new location. This is to make sure that biohazardous material is not released during transportation. The cabinet must be certified again once it's in place.

Regular Certification

Biosafety cabinets should be certified at least once each year.

During Repairs

Movement can disrupt the sterile barrier, so for safety, it's best not to work in an area when a technician is doing repairs unless it's a big open space and the cabinets are a large distance apart.

Disposing of Old Parts 

Following a repair, if you have old/used parts, they can be disposed of in the normal waste stream.

The importance of biosafety cabinet certification cannot be over-emphasized.