Your Guide to Biological Safety Cabinet Testing

Written by ATSC230@545404 on . Posted in WordPress

Labs, healthcare facilities, and manufacturing environments often require the storage, testing, and disposal of biologically hazardous materials. For the protection of personnel and the work environment, biological safety cabinets have been designed and classified to meet certain standards. Depending on the degree of material hazard, these cabinets are fitted with safety mechanisms like air filters and require regular tests to determine their efficacy. We provide cabinet testing and validation, and can help you understand biosafety cabinet classification.

Main Purposes of a Biological Safety Cabinet

Biological safety cabinets are designed to store material and ensure that no contamination between samples or materials in the cabinet and the outside environment and people will occur. When a process or experiment depends on limited environmental factors, keeping contaminants behind a series of physical barriers, hermetically contained until appropriate filtration is achieved, is crucial.

For these safety and logistical reasons, biological safety cabinets have been developed by scientists and utilize many important features to keep them as effective as possible.

Classifications and Their Designs

There are three classifications for biological safety cabinets. Each requires a series of biological safety cabinet testing before they can begin to be used, or as regular validation for their continued use.

Class I and II cabinets are designed to contain low- to moderate-risk biological elements, while Class III contains high-risk elements that can be quite dangerous for personnel and the environment. Both Class I and II require HEPA air filters. However, Class II filters must provide more air security with:

  • Carefully maintained airflow
  • Unidirectional, vertical airflow
  • Filtered exhaust in a designated amount (depending on the sub-classification of the cabinet)

Class III filters take the considerations of Class II much further, having to be gas-tight so that no air contamination takes place. Extra precautions and tests help businesses and labs protect their workers and the integrity of their facilities.


We provide repairs, certification, and testing that is required for different facilities handling hazardous biological materials. Keeping biological cabinets viable is the surest way to keep your business and your employees protected.